Thermo Fisher Scientific Tau Monoclonal Antibody (BT2)
Tau 단백질을 인식하는 BT2 클론의 Mouse Monoclonal 항체로, 인간, 랫드, 원숭이, 소 시료에 반응합니다. Western blot, ELISA, IHC 등 다양한 응용에 적합하며, PHF-Tau와 교차 반응이 없습니다. 고순도(>95%) 및 Low Endotoxin 포뮬레이션으로 연구용에 적합합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | View 7 publications |
| Immunohistochemistry (IHC) | - | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 2 publications |
| ELISA | 2–10 µg/mL | View 13 publications |
| Mass Spectrometry (MS) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Non-human primate, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BT2 |
| Immunogen | Purified bovine Tau (aa 194–198) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
| RRID | AB_10975238 |
Additional Formats
Product Specific Information
MN1010 recognizes normal Tau from human, rat, monkey, and bovine brain.
No cross-reactivity with PHF-Tau has been observed.
The epitope of this antibody has been mapped on human Tau between residues 194 and 198 (RSGYS sequence, Tau40 numbering).
MN1010 detects Tau with a predicted molecular weight of approximately 79 kDa.
This product is a Low Endotoxin formulation.
Purity is >95% as determined by SDS-PAGE.
Target Information
Tau is a neuronal microtubule-associated protein predominantly found on axons.
It promotes tubulin polymerization and stabilizes microtubules.
The C-terminus binds axonal microtubules, while the N-terminus binds neural plasma membrane components, functioning as a linker protein.
Hyper-phosphorylated Tau forms paired helical filaments (PHF), the main component of neurofibrillary tangles in Alzheimer’s disease.
Hyper-phosphorylation impairs Tau’s microtubule binding, leading to neuronal degeneration.
Kinases involved include GSK-3β, PKA, CDK5, and casein kinase II.
Abnormal Tau is also found in Pick’s disease, frontotemporal dementia, corticobasal degeneration, and progressive supranuclear palsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Tau Monoclonal Antibody (HT7), Biotin
640,300원
Thermo Fisher Scientific
Thermo Fisher Scientific Tau Monoclonal Antibody (BT2), Biotin
631,500원
Thermo Fisher Scientific
Thermo Fisher Scientific Tau Monoclonal Antibody (BT2)
599,300원
Thermo Fisher Scientific
Thermo Fisher Scientific CD72 Monoclonal Antibody (10.1.D2), PE
324,600원
Thermo Fisher Scientific
Thermo Fisher Scientific MCP-1 Monoclonal Antibody (E10051)
628,600원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|