Thermo Fisher Scientific FLT3 Monoclonal Antibody (7B7C3)
FLT3 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, WB, IHC, ELISA에 적합합니다. 인간 시료에 반응하며 Protein G 정제 방식으로 제조되었습니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 보관하십시오.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7B7C3 |
| Immunogen | Purified recombinant fragment of human FLT3 (aa: 930–991) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898436 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. Activation occurs through binding of the FLT3 ligand to the extracellular domain, inducing homodimer formation and receptor autophosphorylation. The activated receptor phosphorylates and activates multiple cytoplasmic effector molecules involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Constitutive activation mutations are associated with acute myeloid leukemia and acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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