Thermo Fisher Scientific ADAMTS4 Monoclonal Antibody (OTI2D5), TrueMAB
인간 ADAMTS4 단백질(296-577 aa)에 특이적인 Mouse IgG1 단일클론 항체. Western blot에 1:500 희석으로 검증됨. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 완충액에 보존. -20°C 보관, 연구용 전용.
- 카탈로그번호
- TA805005
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 296–577 of human ADAMTS4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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