Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI1E7), TrueMAB
TYMP 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1E7). Western blot과 IHC(P)에서 검증됨. Human 시료에 반응. 고순도 친화크로마토그래피 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TYMP (Thymidine Phosphorylase), also known as platelet-derived endothelial cell growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate in the presence of inorganic orthophosphate.
It functions as both a chemotactic and mitogenic factor for endothelial cells and acts as a non-heparin binding angiogenic factor found in platelets.
TYMP is also involved in the activation of fluoropyrimidines, cytotoxic agents used in cancer therapy, converting them into active metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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