Thermo Fisher Scientific MEK6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MEK6 (MAP2K6). Validated for Western blot with dilution range 1:500–1:3,000. Recognizes multiple species homologs. Supplied as unconjugated liquid (1 mg/mL). Store at 4°C short term, -20°C long term.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–268 of Human MEK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545803 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (89%), Xenopus laevis (94%), Rhesus Monkey (100%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MKK6 (MEK6, MAP2K6) is a member of the dual specificity protein kinase family, functioning as a mitogen-activated protein (MAP) kinase kinase. MAP kinases act as integration points for multiple biochemical signals. MEK6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress.
This protein is an essential component of the p38 MAP kinase-mediated signal transduction pathway, involved in cellular processes such as stress-induced cell cycle arrest, transcription activation, and apoptosis.
Tissue specificity: Isoform 2 is expressed only in skeletal muscle, while Isoform 1 is found in skeletal muscle, heart, and to a lesser extent in liver and pancreas.
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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