Thermo Fisher Scientific Cetuximab Chimeric Recombinant Mouse Monoclonal Antibody (C225 (Cetuximab))
EGFR을 표적으로 하는 키메라형 마우스 단일클론 항체로, Flow Cytometry 및 Inhibition Assay에 사용 가능. HEK293 세포에서 발현된 재조합 항체이며, 단백질 A로 정제됨. 연구용으로만 사용 가능하며, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Inhibition Assays (IA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | C225 (Cetuximab) |
| Immunogen | The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
Cetuximab (Erbitux) is a chimeric (mouse/human) monoclonal antibody approved by the U.S. Food and Drug Administration for the treatment of patients with metastatic colorectal cancer, metastatic non-small cell lung cancer, and head and neck cancer. Cetuximab, as an epidermal growth factor receptor (EGFR) inhibitor, binds to EGFR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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