Thermo Fisher Scientific CCL5 (RANTES) Polyclonal Antibody
Rat RANTES(CCL5)을 인식하는 Rabbit Polyclonal Antibody로, WB 및 ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제된 Lyophilized 형태. 연구용으로 HIV 억제 관련 면역반응 연구에 적합.
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Thermo Fisher Scientific CCL5 (RANTES) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL |
| ELISA | 0.5–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant protein corresponding to rat RANTES |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2071437 |
Product Specific Information
Reconstitute with 0.1 mL of distilled water. For long-term storage, the addition of 0.09% sodium azide is recommended.
Prior to reconstitution, store at 4°C. After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles.
Rabbit anti-Rat RANTES antibody recognizes rat RANTES (CCL5), a chemoattractant for blood monocytes, memory T-helper cells, and eosinophils.
Target Information
CCL5 (RANTES) is a chemokine gene located on chromosome 17q. Chemokines are secreted proteins involved in immunoregulatory and inflammatory processes, divided into four subfamilies by the arrangement of N-terminal cysteine residues.
CCL5 functions as a chemoattractant for blood monocytes, memory T-helper cells, and eosinophils, induces histamine release from basophils, and activates eosinophils. It is one of the major HIV-suppressive factors produced by CD8+ cells and acts as a natural ligand for CCR5, suppressing replication of HIV-1 R5 strains.
Alternative splicing results in multiple transcript variants encoding different isoforms.
Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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