Thermo Fisher Scientific CCL5 (RANTES) Polyclonal Antibody

Thermo Fisher Scientific CCL5 (RANTES) Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Reconstitute with 0.1 mL of distilled water. For long-term storage, the addition of 0.09% sodium azide is recommended.
Prior to reconstitution, store at 4°C. After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles.

Rabbit anti-Rat RANTES antibody recognizes rat RANTES (CCL5), a chemoattractant for blood monocytes, memory T-helper cells, and eosinophils.

Target Information

CCL5 (RANTES) is a chemokine gene located on chromosome 17q. Chemokines are secreted proteins involved in immunoregulatory and inflammatory processes, divided into four subfamilies by the arrangement of N-terminal cysteine residues.
CCL5 functions as a chemoattractant for blood monocytes, memory T-helper cells, and eosinophils, induces histamine release from basophils, and activates eosinophils. It is one of the major HIV-suppressive factors produced by CD8+ cells and acts as a natural ligand for CCR5, suppressing replication of HIV-1 R5 strains.
Alternative splicing results in multiple transcript variants encoding different isoforms.
Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.