Thermo Fisher Scientific CD177 Polyclonal Antibody
CD177 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 최적화. 인간과 랫트 시료에 반응하며, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: 참고 문헌 보기
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: 참고 문헌 보기
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD177 (Accession Q8N6Q3), corresponding to amino acid residues L298–A348 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850216 |
Product Specific Information
Antibody detects endogenous levels of total CD177.
Target Information
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein mainly present on neutrophils. Its plasma membrane expression increases during pregnancy, inflammation, or after G-CSF application. The ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and acts as a pro-proliferative molecule. Antibodies against CD177 may be involved in neonatal alloimmune neutropenia (NAN).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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