Thermo Fisher Scientific MTCH2 Polyclonal Antibody
Rabbit polyclonal antibody against human MTCH2 protein. Validated for IHC (paraffin) with dilution 1:20–1:50. Purified via antigen affinity chromatography. Supplied in PBS with 40% glycerol and 0.02% sodium azide. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MTCH2. Recombinant protein control fragment (Product # RP-97277) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644246 |
Product Specific Information
Immunogen sequence:
VGYEPLPPTI GRNIFGRQVC QLPGLFSYAQ HIASIDGRRG LFTGLTPRLC SGVLGTVVHG KVLQHYQESD KGEELGP
Sequence identity:
- Mouse: 94%
- Rat: 88%
Target Information
MTCH2 is a member of the mitochondrial carrier protein family that catalyzes the exchange of substrates across the inner mitochondrial membrane. It is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis is crucial for organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process is linked to diseases such as cancer. The Bcl-2 family includes both apoptosis inhibitors and promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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