Thermo Fisher Scientific Phospho-EEF2K (Ser359) Polyclonal Antibody
Rabbit polyclonal antibody specific for phosphorylated EEF2K (Ser359). Validated for IHC (paraffin) at 1:50–1:100 dilution. Useful in studying protein synthesis regulation and cancer-related kinase signaling. Supplied as liquid, 1 mg/mL, stored at -20°C.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human eEF2K around the phosphorylation site of Ser359 (G-SP-P-R-V) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2556337 |
Target Information
EEF2K is a highly conserved serine/threonine kinase in the calmodulin signaling pathway whose activity is increased in cancers including breast cancer.
EEF2K (eukaryotic elongation factor 2 kinase) regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by upstream kinases such as AMPK or TRPM7, EEF2K phosphorylates elongation factor EEF2 at a single site, rendering it unable to bind ribosomes and thereby reducing the rate of protein synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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