Thermo Fisher Scientific Phospho-Atypical Chemokine Receptor 2 (Ser348, Ser350) Polyclonal Antibody
인간 ACKR2 단백질의 Ser348/Ser350 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 1 mg/mL 농도. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human ACKR2 around the phosphorylation site of Ser348/Ser350 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
This gene encodes a beta chemokine receptor, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for recruitment of effector immune cells to inflammation sites.
The gene is expressed in various tissues and hemopoietic cells. Expression in lymphatic endothelial cells and overexpression in vascular tumors suggest a role in chemokine-driven leukocyte recirculation and vascular tumor development.
It binds most beta-chemokine family members, though its specific function remains unclear. The gene is mapped to chromosome 3p21.3, within a cluster of chemokine receptor genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: 7TM0314A_CCRD6_O00590-1_Rabbit.svg, 7TM0314A_CCRD6_O00590-1_Rabbit_PDP.jpeg)
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