Thermo Fisher Scientific ETV4 Polyclonal Antibody
ETV4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간, 생쥐, 랫트에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%) 제품으로 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human ETV4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719573 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
ETV4 (ets variant gene 4, also known as E1A enhancer binding protein or PEA3) is a member of the Ets gene family encoding sequence-specific DNA binding proteins.
These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2, and rat GABP-α.
All Ets proteins recognize similar DNA motifs with a central 5'-GGAA-3' element.
PEA3 binds the motif 5'-AGGAAG-3' (PEA-3 motif) but does not bind 5'-AGGAAC-3', which is recognized by PU.1.
Each Ets protein interacts with unique sequences flanking the core motif.
PEA3 is expressed in epithelial and fibroblastic cells but not in hematopoietic cells, unlike Ets-1, Ets-2, and Fli-1, which are primarily expressed in hematopoietic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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