Thermo Fisher Scientific REV1 Polyclonal Antibody
REV1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간 및 생쥐 시료 반응성. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Thermo Fisher Scientific REV1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human REV1 (Accession Q9UBZ9), corresponding to amino acid residues Q1219–T1251 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850367 |
Product Specific Information
Antibody detects endogenous levels of total REV1.
Target Information
This gene encodes a protein similar to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, important for protein-protein interactions. The human Rev1-like protein likely acts as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants encoding different proteins have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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