Thermo Fisher Scientific LDLR Monoclonal Antibody (02)
인간 LDL 수용체(LDLR)에 특이적인 마우스 단클론 항체로 ELISA에 적합합니다. 보존제가 없는 액상 형태이며 Protein A로 정제되었습니다. 4°C 단기 보관, 장기 보관은 -20°C에서 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:250–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 02 |
| Immunogen | Recombinant Human LDLR/LDL R/LDL Receptor Protein (Met1–Arg788) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786338 |
Product Specific Information
- This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human LDLR/LDL R/LDL Receptor.
Target Information
The low density lipoprotein receptor (LDL-R) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL binds at the cell membrane and is internalized to lysosomes, where the protein is degraded and cholesterol becomes available for repression of HMG CoA reductase, the rate-limiting enzyme in cholesterol synthesis. Mutations in the LDL-R gene cause familial hypercholesterolemia. LDL-R also acts as an entry factor for Hepatitis C virus along with SCARB1, CLDN1, and CD81. At least three isoforms of LDL-R are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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