Thermo Fisher Scientific IGFBP7 Polyclonal Antibody
IGFBP7 단백질을 특이적으로 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 고순도 친화 크로마토그래피 정제, PBS/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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- PA5102670
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카탈로그
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Thermo Fisher Scientific IGFBP7 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IGFBP7 (Accession Q16270), corresponding to amino acid residues G174–P224 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852067 |
Product Specific Information
Antibody detects endogenous levels of total IGFBP7.
Target Information
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family.
IGFBPs bind IGFs with high affinity, regulate IGF availability in body fluids and tissues, and modulate IGF binding to its receptors.
IGFBP7 binds IGF-I and IGF-II with relatively low affinity and belongs to a subfamily of low-affinity IGFBPs.
It also stimulates prostacyclin production and cell adhesion.
Alternatively spliced transcript variants encoding different isoforms have been described, and one variant has been associated with retinal arterial macroaneurysm.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-102670_IGFBP7_Q16270-1_Rabbit.svg, PA5-102670_IGFBP7_Q16270-1_Rabbit_PDP.jpeg)
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