Thermo Fisher Scientific Ataxin 7 Polyclonal Antibody

Thermo Fisher Scientific Ataxin 7 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000 dilution

Product Specifications

Product Specific Information

Predicted to react with mouse samples.

Target Information

Spinocerebellar ataxia type 7 (SCA7) is a hereditary neurodegenerative disease characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem, leading to dementia, macular degeneration, and other neurodegenerative symptoms.
The SCA7 gene encodes the 892-residue protein ataxin-7, typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. Mutations in the SCA7 gene cause ataxin-7 to accumulate in intranuclear inclusions, potentially resulting in neuronal cell death.

Usage Note

For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.

제품 이미지

(PA5-68099_Ataxin_7_O15265-1_Rabbit_PDP.jpeg 및 관련 항원 구조 이미지 포함)