Thermo Fisher Scientific Ataxin 7 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Ataxin 7, suitable for Western blot applications. Predicted cross-reactivity with mouse samples. Supplied as a liquid, unconjugated form at 1 mg/mL concentration. For research use only.
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Thermo Fisher Scientific Ataxin 7 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Ataxin 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691865 |
Product Specific Information
Predicted to react with mouse samples.
Target Information
Spinocerebellar ataxia type 7 (SCA7) is a hereditary neurodegenerative disease characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem, leading to dementia, macular degeneration, and other neurodegenerative symptoms.
The SCA7 gene encodes the 892-residue protein ataxin-7, typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. Mutations in the SCA7 gene cause ataxin-7 to accumulate in intranuclear inclusions, potentially resulting in neuronal cell death.
Usage Note
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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(PA5-68099_Ataxin_7_O15265-1_Rabbit_PDP.jpeg 및 관련 항원 구조 이미지 포함)
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