Thermo Fisher Scientific TGF beta 2 Polyclonal Antibody
TGF beta 2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며 Protein A로 정제된 액상 형태입니다. 연구용으로 세포 신호전달 및 발달 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human TGF beta 2, amino acids 351–414 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transforming Growth Factor (TGF) betas mediate numerous cell-to-cell interactions during embryonic development. Three isoforms (TGF beta 1, 2, and 3) are synthesized as precursor proteins that are cleaved to yield a 112 amino acid polypeptide associated with a latent portion of the molecule.
TGF betas are multifunctional, influencing cell proliferation, differentiation, and various cellular functions. They are produced by both transformed and non-neoplastic tissues, and nearly all mammalian cells possess specific TGF receptors.
- Cells of mesenchymal origin are generally stimulated by TGF beta.
- Cells of epithelial or neuroectodermal origin are typically inhibited by TGF beta.
- TGF beta 2 is found abundantly in porcine platelets and mammalian bone.
- Latent TGF beta 2 is the main isoform in body fluids such as amniotic fluid, breast milk, and ocular humors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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