Thermo Fisher Scientific DARC Polyclonal Antibody, Biotin
Human DARC 단백질을 인식하는 Goat 유래 Polyclonal Antibody로, Biotin 결합형입니다. Western blot, IHC, Flow cytometry 등 다양한 응용 가능. 0.5 mg/mL 농도의 액상 시약으로, TBS(pH 7.3) 및 BSA 포함. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DARC Polyclonal Antibody, Biotin
Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence: HRAELSPSTENSSQLDFEDC |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932837 |
Product Specific Information
- Expected to recognize both reported isoforms (NP_001116423.1; NP_002027.2).
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
ACKR1 (also known as DARC) is an atypical chemokine receptor that regulates chemokine levels and localization through high-affinity binding, independent of classical signal transduction. It functions in chemokine sequestration, degradation, or transcytosis.
ACKR1 binds inflammatory chemokines of both CXC and CC subfamilies but not homeostatic chemokines. It also serves as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC, and for malaria parasites P. vivax and P. knowlesi.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.