Thermo Fisher Scientific Phospho-Ezrin (Tyr353) Polyclonal Antibody
Human Ezrin 단백질의 Tyr353 인산화 부위를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 검증 완료. Moesin 및 Radixin과 교차 반응 없음. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr353 of human Ezrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 71 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979996 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with phosphorylated Moesin or Radixin.
Target Information
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, it serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration, and organization, and has been implicated in various human cancers.
A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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