Thermo Fisher Scientific ACVRL1 Polyclonal Antibody
ACVRL1 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 및 생쥐 시료에 반응합니다. Western blot, IHC, Flow cytometry 등 다양한 응용에 적합합니다. 고순도 정제 및 안정적인 액상 형태로 제공되며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 38–68 amino acids from the N-terminal region of human ACVRL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2222472 |
Target Information
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1 has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich GS domain preceding the kinase domain, and a short C-terminal tail.
Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2 and have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by bone formation in muscles, tendons, and connective tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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