Thermo Fisher Scientific MAP2 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MAP2 (NP_114033.2, 1 a.a. approximately 471 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAP2,uniProtId:P11137-1,ncbiNodeId:9606,antigenRange:1-1827,antigenLength:1827,antigenImageFileName:H00004133-D01P_MAP2_P11137-1_Rabbit.svg,antigenImageFileNamePDP:H00004133-D01P_MAP2_P11137-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MADERKDEAK APHWTSAPLT EASAHSHPPE IKDQGGAGEG LVRSANGFPY REDEEGAFGE HGSQGTYSNT KENGINGELT SADRETAEEV SARIVQVVTA EAVAVLKGEQ EKEAQHKDQT AALPLAAEET ANLPPSPPPS PASEQTVTVE EAAGGESALA PSVFKQAKDK VSDGVTKSPE KRSSLPRPSS ILPPRRGVSG DRDENSFSLN SSISSSARRT TRSEPIRRAG KSGTSTPTTP GSTAITPGTP PSYSSRTPGT PGTPSYPRTP HTPGTPKSAI LVPSEKKVAI IRTPPKSPAT PKQLRLINQP LPDLKNVKSK IGSTDNIKYQ PKGGQVQIVT KKIDLSHVTS KCGSLKNIRH RPGGGRVKIE SVKLDFKEKA QAKVGSLDNA HHVPGGGNVK IDSQKLNFRE HAKARVDHGA EIITQSPGRS SVASPRRLSN VSSSGSINLL ESPQLATLAE DVTAALAKQG L

Target Information

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer`s Disease (AD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.