Thermo Fisher Scientific Inhibin, alpha (INHA) Monoclonal Antibody (INHA, 4266)
Human INHA 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, IHC(P) 실험에 적합합니다. 200 µg/mL 농도의 액상 형태이며 Protein A/G로 정제되었습니다. PBS 버퍼에 BSA와 sodium azide가 포함되어 있으며 4°C에서 보관합니다.
- 카탈로그번호
- 3623-MSM6-P1
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | INHA, 4266 |
| Immunogen | A synthetic peptide (around aa73–96) of the α-subunit of human inhibin A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor.
Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity.
Serum levels of inhibin reflect the size of granulosa-cell tumors and can be used as a marker for primary and recurrent disease.
In prostate cancer, expression of the inhibin alpha-subunit gene is suppressed and undetectable in poorly differentiated tumor cells.
Expression varies tissue-specifically, suggesting inhibin acts as both a growth/differentiation factor and a hormone.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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