Thermo Fisher Scientific Human SHP2 Synthetic Peptide
인간 SHP2 단백질의 N-말단 14개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-20279와 함께 차단 펩타이드로 사용 가능하며, PBS 기반 완충액에 보관됩니다. 세포 신호 조절 연구용으로 적합합니다.
- 카탈로그번호
- PEP0409
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the amino terminus of human SHP2.
PEP-0409 can be used as a blocking peptide with polyclonal antibody PA5-20279.
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 (SH2) domains, which function as phospho-tyrosine binding domains and mediate substrate interactions.
It is widely expressed in most tissues and plays a regulatory role in diverse signaling events such as mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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