Thermo Fisher Scientific RPS3 Recombinant Rabbit Monoclonal Antibody (SA46-08)
RPS3 단백질을 인식하는 재조합 토끼 단클론 항체로 Western blot, IHC, ICC/IF에 적합합니다. 높은 특이성과 재현성을 제공하며, Protein A로 정제된 액상 형태입니다. 인간, 마우스, 랫트 시료에 반응하며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SA46-08 |
| Immunogen | Synthetic peptide within Human RPS3 aa 125–174 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809267 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broad immunoreactivity due to the larger rabbit immune repertoire
Target Information
WD repeat domain 5 (WDR5) is a member of the WD repeat protein family involved in various cellular processes such as cell cycle progression, signal transduction, apoptosis, and gene regulation.
WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development.
It interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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