Thermo Fisher Scientific ZIPK Polyclonal Antibody
ZIPK 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 사용 가능. Human과 Mouse에서 반응하며, 항원 친화 크로마토그래피로 정제됨. 세포 이동성 및 사멸 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of Human Zipper-Interacting Protein Kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
DAPK3 is a serine/threonine kinase functionally linked to cell motility, smooth muscle contractility, and cell death processes.
DAPK3 is encoded by ZIPK and is a component of desmosomes and the epidermal cornified envelope in keratinocytes.
The N-terminal domain interacts with the plasma membrane, while the C-terminus interacts with intermediate filaments.
Through its rod domain, this protein forms complexes with envoplakin, potentially linking the cornified envelope, desmosomes, and intermediate filaments.
AKT1/PKB, a protein kinase mediating cell growth and survival signaling, interacts with this protein, suggesting a role as a localization signal in AKT1-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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