Thermo Fisher Scientific ZFYVE19 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ZFYVE19 (AAH21092.1, 1 a.a. approximately 328 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZFYVE19,uniProtId:Q96K21-1,ncbiNodeId:9606,antigenRange:1-471,antigenLength:471,antigenImageFileName:H00084936-D01P_ZFYVE19_Q96K21-1_Rabbit.svg,antigenImageFileNamePDP:H00084936-D01P_ZFYVE19_Q96K21-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MESRCYGCAV KFTLFKKEYG CKNCGRAFRS GCLSFSAAVP RTGNTQQKVC KQCHEVLTRG SSANASKWSP PQNYKKRVAA LEAKQKPSTS QSQGLTRQDQ MIAERLARLR QENKPKLVPS QAEIEARLAA LKDERQGSIP STQEMEARLA ALQGRVLPSQ TPQPAHHTPD TRTQAQQTQD LLTQLAAEVA IDESWKGGGP VTLQDYRLPD SDDDEDEETA IQRVLQQLTE EAALDEASGF NIPAEQASRP WTQPRGAEPE AQDVDPRPEA EEEELPWCCI CNEDATLRCA GCDGDLFCAR CFREGHDAFE LKEHQTSAYS PPRAGQEH

Target Information

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.