Thermo Fisher Scientific RNF2 Polyclonal Antibody
RNF2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC, IP, ChIP 등 다양한 응용에 적합. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RNF2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
| ChIP assay (ChIP) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human RNF2 (amino acids 1–336, UniProt ID: Q99496-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720485 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
RNF2 (E3 ubiquitin-protein ligase RING2) mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub), playing a central role in histone code and gene regulation. Its ligase activity is enhanced by BMI1/PCGF4. H2AK119Ub serves as a marker for epigenetic transcriptional repression and participates in X chromosome inactivation in female mammals. RNF2 is a core component of the Polycomb group (PcG) PRC1-like complex, essential for maintaining transcriptional repression of developmental genes such as Hox genes through chromatin remodeling and histone modification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.