Thermo Fisher Scientific Amylin Polyclonal Antibody
Thermo Fisher Scientific의 Amylin Polyclonal Antibody는 인간 Amylin 단백질을 인식하는 Rabbit IgG 항체로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고농도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 17–89 of Human Amylin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.83 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2547187 |
Product Specific Information
- Recommended positive control: AsPC1
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Islet, or insulinoma, amyloid polypeptide (Amylin) is commonly found in pancreatic islets of patients suffering from type II diabetes mellitus or harboring an insulinoma. While the association of Amylin with type II diabetes has been known for some time, its direct causative role remains unclear. Studies suggest that Amylin, similar to beta-amyloid (Abeta) involved in Alzheimer’s disease, can induce apoptotic cell death in cultured cells, potentially contributing to type II diabetes development.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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