Thermo Fisher Scientific LIMD1 Polyclonal Antibody
LIMD1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합. Human 시료 반응성, 항원 친화 크로마토그래피로 정제. 액상 형태로 4°C 보관, 연구용으로만 사용.
- 카탈로그번호
- A303182A
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of human LIM Domains Containing 1 (LIMD1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6, and Zyxin.
Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing three LIM zinc-binding domains.
LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions.
Limd1 interacts with the proteins SQSTM1, Rb, p62, and TRAF6.
Limd1 was first identified when deletion of its gene was noted in some cervical cancers.
It blocks in vitro and in vivo tumor growth and is downregulated in lung cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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