Thermo Fisher Scientific Caspase 3 Recombinant Rabbit Monoclonal Antibody (23GB705)
Caspase 3 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot과 유세포분석에 최적화됨. HEK293F에서 발현되었으며, 고순도 친화 크로마토그래피로 정제. 인간 Caspase 3 연구용으로 사용되며, -20°C에서 보관.
- 카탈로그번호
- MA55420x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Caspase 3 Recombinant Rabbit Monoclonal Antibody (23GB705)
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB705 |
| Immunogen | A synthetic peptide of human Caspase 3 (52–120 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, which dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7, and 9, and is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, associated with neuronal death in Alzheimer’s disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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