Thermo Fisher Scientific OST4 Polyclonal Antibody
Thermo Fisher Scientific의 OST4 Polyclonal Antibody는 인간 OST4 단백질을 표적으로 하는 토끼 IgG 항체입니다. Western blot에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 안정적인 저장 및 높은 종 간 상동성을 보입니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human OST4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690107 |
Product Specific Information
This target displays homology in the following species:
- Dog: 83%
- Human: 100%
- Mouse: 100%
- Rat: 100%
- Zebrafish: 93%
Target Information
OST4 is a subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. This is the first step in protein N-glycosylation, which occurs cotranslationally. The OST complex associates with the Sec61 translocon complex in the endoplasmic reticulum (ER) to mediate protein translocation. All subunits are required for maximal enzyme activity, and OST4 is specifically involved in maintaining stability of STT3A-containing OST complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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