Thermo Fisher Scientific PER2 Polyclonal Antibody
PER2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 0.02% sodium azide 포함. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Partial synthetic peptide corresponding to an internal portion of the human PER2 protein (amino acids 100–150) [UniProt# O15055] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term); for long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2161674 |
Product Specific Information
Peptide 1 has 94% sequence homology with rat, and peptide 2 has 94% sequence homology with rat and mouse.
Target Information
PER2 (Period circadian protein homolog 2) is a mainly nuclear protein involved in circadian rhythm regulation. It belongs to the basic helix-loop-helix family of transcription factors and contains PAC and PAS domains. PER2 is part of the circadian core oscillator complex, including CRY, CLOCK/NPAS2, BMAL1/2, CSNK1D/E, TIMELESS, and other PER proteins. It plays a critical role in generating circadian rhythms and acts as a negative regulator in the transcriptional feedback loop. PER2 is strongly expressed in skeletal muscle and pancreas, with lower expression in the lung. Mutations in PER2 are associated with familial advanced sleep-phase syndrome (FASPS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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