Thermo Fisher Scientific SETD7 Recombinant Rabbit Monoclonal Antibody (001)
Human SETD7 단백질을 인식하는 재조합 토끼 단클론 항체. ELISA에 최적화되어 있으며 높은 특이성과 일관된 로트 간 재현성을 제공. 보존제 무첨가로 필요 시 sodium azide 추가 권장. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilution
- Application: ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 001 |
| Immunogen | Recombinant Human SETD7/SET7/9 protein (Asp2–Lys366) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786548 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the large rabbit immune repertoire
This antibody has specificity for Human SETD7/SET7/9.
Target Information
Histone methyltransferase that specifically monomethylates Lys-4 of histone H3. H3 Lys-4 methylation acts as an epigenetic transcriptional activation tag. Plays a central role in activating genes such as collagenase and insulin. Recruited by IPF1/PDX-1 to the insulin promoter to activate transcription. Also methylates non-histone proteins such as p53/TP53, TAF10, and possibly TAF7, enhancing transcriptional activity and protein stability.
[UniProt]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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