Thermo Fisher Scientific MTMR4 Polyclonal Antibody
MTMR4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 실험에 사용 가능. Human과 Mouse 반응성 확인됨. 0.5 mg/mL 농도의 액상 형태로 제공되며, PBS buffer(0.09% sodium azide 포함)에 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1155–1187 amino acids from the C-terminal region of human MTMR4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Size-exclusion - Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2147962 |
Target Information
MTMR, a member of the myotubularin family, encodes an intracellular protein of 1,195 amino acids and shares approximately 47% sequence identity with MTMR3, increasing to over 70% identity in the catalytic domain and the double zinc finger (FYVE) motif.
PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus.
Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3.
MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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