Thermo Fisher Scientific FAM212A Polyclonal Antibody
FAM212A 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS와 글리세롤 용액 형태로 제공. 신경능선세포 관련 연구에 적합. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM212A. Recombinant protein control fragment (Product # RP-100269) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641373 |
Product Specific Information
Immunogen sequence:
WDSGFSEVSG STWREEELPV SQRPAPSAQP LRRQCLSVSG LPMPSRAPVA SVPPVHHPRP KSTPDACLEH WQGLEAEDWT AALLNRGRS
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 76%
- Rat: 76%
Target Information
FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in Xenopus, is expressed primarily in neural crest cells and their derivatives.
FAM212A can associate with the P21-kinase protein PAK4, modulating cytoskeletal dynamics.
In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A- mice exhibited exencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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