Thermo Fisher Scientific LOX-1 Polyclonal Antibody
Thermo Fisher Scientific의 LOX-1 Polyclonal Antibody는 Mouse LOX-1을 인식하는 Goat 유래 IgG 항체로, Western blot과 중화 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, Lyophilized 형태로 제공되어 안정적 보관이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1 µg/mL
Neutralization (Neu)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse LOX-1 (Arg60–Ile363) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605573 |
Product Specific Information
- This antibody can block receptor-ligand interaction in a functional ELISA assay.
- In Western blots, approximately 5% cross-reactivity with recombinant human LOX-1 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
LOX-1 (lectin-like oxidized LDL receptor-1) is a 40–50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets, and smooth muscle cells.
LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite-modified high-density lipoprotein (HDL), aged/apoptotic cells, activated platelets, and bacteria, reflecting its versatile physiological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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