Thermo Fisher Scientific Protein C Polyclonal Antibody
Thermo Fisher Scientific의 Protein C Polyclonal Antibody는 인간 및 마우스 시료에서 Protein C를 검출하는 데 사용됩니다. Western blot과 ELISA에 적합하며, 비결합형 액상 항체로 SDS-PAGE 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 25 µg/mL |
| ELISA | 5–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Murine Protein C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2172290 |
Product Specific Information
PA1-43064 detects Protein C in mouse samples.
It has been successfully used in Western blot and ELISA applications.
This antibody was derived from mouse Protein C.
Target Information
Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex. In its activated form, Protein C contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII.
Protein C is produced in the liver and composed of two polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor, and the active enzyme (55 kDa) cleaves factor Va and VIIIa, thereby inhibiting blood coagulation.
Normal concentrations in human plasma are approximately 1–3 ng/mL for the active enzyme and about 3 µg/mL for the proenzyme due to rapid turnover. Mutations in the Protein C gene have been associated with thrombophilia due to Protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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