Thermo Fisher Scientific HHEX Monoclonal Antibody (4E9)
HHEX 단백질을 인식하는 Mouse IgG2a 단클론 항체. Western blot 및 ELISA에 적합하며, 인간 시료에 반응. PBS 완충액에 보존되며 방부제 미함유. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E9 |
| Immunogen | HHEX (NP_002720, 133 a.a. – approximately 237 a.a) full length recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PLHKRKGGQV RFSNDQTIEL EKKFETQKYL SPPERKRLAK MLQLSERQVK TWFQNRRAKW RRLKQENPQS NKKEELESLD SSCDQRQDLP SEQNKGASLD SSQCS
Target Information
HHEX is a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. It establishes anterior identity at two levels:
- Acts early to enhance canonical WNT-signaling by repressing expression of TLE4.
- Acts later to inhibit NODAL-signaling by directly targeting NODAL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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