Thermo Fisher Scientific USP35 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human and non-human primate USP35 단백질. Western blot 및 Immunocytochemistry에 적합하며, 1 mg/mL 농도의 액상 형태로 제공. Affinity chromatography로 정제되었으며, -20°C에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human USP35 (Accession Q9P2H5), corresponding to amino acid residues S977–F1018 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900744 |
Product Specific Information
Antibody detects endogenous levels of total USP35.
Target Information
p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence-specific DNA binding, interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to genotoxic stresses such as UV irradiation or DNA damage, p53 is expressed and undergoes post-translational modification, leading to nuclear accumulation. Activation of p53 can result in cell cycle arrest or apoptosis, preventing proliferation of genetically damaged cells. Thus, p53-dependent pathways help maintain genomic stability by eliminating damaged cells. Accumulation of high levels of p53 is a potential marker for malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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