Thermo Fisher Scientific PUS7 Polyclonal Antibody
PUS7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 사용 가능. Human PUS7의 100–150번 잔기 영역을 항원으로 제작. 액상 형태, 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:10,000–1:25,000 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 100 to 150 of Human Pseudouridylate synthase 7 homolog |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141, PubMed:30778726).
Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141).
Also catalyzes pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919).
In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs, and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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