Thermo Fisher Scientific DUSP5 Monoclonal Antibody (OTI1D8), TrueMAB
인간 DUSP5 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. 고순도의 액상 형태로 제공되며, 1 mg/mL 농도로 PBS, BSA, 글리세롤 기반 버퍼에 보관됩니다. ERK1 비활성화 연구 등 MAPK 신호전달 관련 연구에 적합합니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 125–384 of human DUSP5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the dual specificity protein phosphatase (DUSP) subfamily. These phosphatases inactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase (MAPK) superfamily, which are associated with cellular proliferation and differentiation.
Different members of the DUSP family show distinct substrate specificities for various MAP kinases, tissue distribution, subcellular localization, and inducibility by extracellular stimuli. DUSP5 inactivates ERK1, is expressed in various tissues (notably in pancreas and brain), and is localized in the nucleus.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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