Thermo Fisher Scientific Bu-1a Monoclonal Antibody (21-1A4)
닭 Bu-1a 항원을 인식하는 Mouse IgG1 단일클론 항체로, Flow Cytometry에 사용 가능. 비결합형 액상 제품이며 0.5 mg/mL 농도로 제공. 연구용으로만 사용되며 4°C에서 보관.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1 µg/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 21-1A4 |
| Immunogen | Bursa cells from one-day-old H.B15 (Bu-1a/b) strain chickens |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with proprietary stabilizer |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745714 |
Additional Formats
Target Information
Bu-1, a product of the Bu-1a and Bu-1b alleles, is a type I transmembrane glycosylated disulfide-linked homodimer.
The monoclonal antibody AV20 recognizes a monomorphic determinant on the Bu-1 B cell-associated alloantigens of both RPL 6(3) (Bu-1a) and 7(2) (Bu-1b) lines of inbred chickens.
The antibody also identifies B cells in partially inbred birds. Bu-1 is found on 85–90% of bursal cells, 2–8% of thymocytes, 15–27% of spleen cells, and 2–18% of peripheral blood cells.
It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes.
The monoclonal antibody AV20 does not cross-react with turkey cells when analyzed by flow cytometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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