Thermo Fisher Scientific KPNA2 Polyclonal Antibody
Thermo Fisher Scientific의 KPNA2 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 Rabbit IgG 항체입니다. Western blot 및 IHC에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 냉장 보관(2–8°C) 및 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 5 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human KPNA2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153556 |
Product Specific Information
- Suggested positive control: rat heart tissue lysate
- PA5-21034 can be used with blocking peptide PEP-1148
Target Information
The import of proteins into the nucleus is a process that involves at least two steps:
- An energy-independent docking of the protein to the nuclear envelope
- An energy-dependent translocation through the nuclear pore complex
Imported proteins require a nuclear localization sequence (NLS) consisting of short regions of basic amino acids. Proteins involved in the first step of nuclear import include Xenopus importin and its yeast homolog SRP1, which bind to the NLS.
KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in VJ recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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