Thermo Fisher Scientific IL-2 Monoclonal Antibody (7H11AB7)
ELISA, Western blot, Flow cytometry, Immunoprecipitation에 적합한 Rat IL-2 단클론 항체. Mouse IgG1 형식으로 Protein A 정제. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | 5 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7H11AB7 |
| Immunogen | Full length recombinant rat IL-2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.2 |
| Contains | 0.1% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536410 |
Product Specific Information
This monoclonal antibody is suitable for use in ELISA applications as a capture antibody and in immunoprecipitation assays. Purity is >95% as determined by SDS-PAGE analysis.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by IL-4 and IL-7. The expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism. Disruption of an IL-2-like gene in mice leads to ulcerative colitis-like disease, indicating its essential role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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