Thermo Fisher Scientific HOXB4 Polyclonal Antibody
HOXB4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 마우스 반응성, Western blot과 ELISA에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 저장 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acids 50–150 of human HOXB4 (NP_0769201) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.16 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901330 |
Product Specific Information
- Positive Samples: HL-60, Mouse liver
- Immunogen sequence:
PEAGFGRRAA CTVQRYAACR DPGPPPPPPP PPPPPPPPGL SPRAPAPPPA GALLPEPGQR CEAVSSSPPP PPCAQNPLHP SPSHSACKEP VVYPWMRKVH V
Target Information
HOX homeobox genes play a role both in early stem cell function and in later stages of hematopoietic differentiation.
HOXB4 is a homeotic selector gene implicated in self-renewal of definitive hematopoietic stem cells (HSCs).
Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induces a switch to the definitive HSC phenotype.
Activation of WNT signaling in HSCs increases expression of HOXB4.
Perturbations of HOX gene expression can cause leukemia.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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