Thermo Fisher Scientific CD5 Recombinant Rabbit Monoclonal Antibody (039)

Applications

Flow Cytometry (Flow)

• Tested Dilution: 1:25–1:100

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Additional Formats

• APC
• FITC
• PE
• PerCP
• Request custom conjugation

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Human CD5.

Target Information

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation.

• Found on 95% of thymocytes and 72% of peripheral blood lymphocytes
• Main reactivity in lymph node T cell areas
• Expressed by many T cell leukemias, lymphomas, and activated T cells
• Associated diseases: thymus cancer, Richter’s Syndrome

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.