Thermo Fisher Scientific HOXC12 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human HOXC12(Accession P31275), corresponding to amino acid residues P65-D115. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HOXC12,uniProtId:P31275-1,ncbiNodeId:9606,antigenRange:65-115,antigenLength:282,antigenImageFileName:PA5-103893_HOXC12_P31275-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103893_HOXC12_P31275-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853225

Product Specific Information

Antibody detects endogenous levels of total HOXC12.

Target Information

The Homeobox (Hox) proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. In mammals, there are four gene clusters encoding Hox proteins, namely HoxA, HoxB, HoxC and HoxD, that are located on different chromosomes, each consisting of 9-11 tandemly arranged genes. HoxC12 (Homeobox C12), also known as Hox3, Hox3F or HOC3F, is a member of the Abd-B homeobox (Hox) family and is encoded by a gene from the HoxC cluster. HoxC12 is a 282 amino acid long nuclear protein that contains one homeobox DNA-binding domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.