Thermo Fisher Scientific LRP12 Polyclonal Antibody
Human LRP12 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. Antigen affinity chromatography로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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- PA553568
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LRP12. Recombinant protein control fragment (Product #RP-90323) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643475 |
Product Specific Information
Immunogen sequence:
FPVCSPNQAS VLENLRLAVR SQLGFTSVRL PMAGRSSNIW NRIFNFARSR HSGSLALVSA DGDEVVPSQS TSREPERNHT HRSLFSVESD DTDTENERRD MAGASGGVAA PLPQKVPPTT AVEATVGACA SSS
Antigen sequence identity:
- Mouse: 90%
- Rat: 89%
Target Information
Members of the LDL receptor gene family, including LDLR, LRP1, Megalin (GP330), VLDLR, and ApoER2, are characterized by cysteine-rich class A repeats, EGF-like repeats, YWTD repeats, and an O-linked sugar domain.
LRP12 (also designated ST7) is a member of the LDLR family involved in internalization of lipophilic molecules and/or signal transduction.
LRP12 interacts with RACK1, MADHIP, and Integrin beta-1-binding protein 3, and is widely expressed in heart, skeletal muscle, brain, lung, placenta, and pancreas.
Overexpression may be associated with oral tumors, suggesting LRP12 as a potential oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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