Thermo Fisher Scientific STOML2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 29-356 of human STOML2 (NP_0384701) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:STOML2,uniProtId:Q9UJZ1-1,ncbiNodeId:9606,antigenRange:29-356,antigenLength:356,antigenImageFileName:PA5-87867_STOML2_Q9UJZ1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87867_STOML2_Q9UJZ1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.95 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804468

Product Specific Information

Immunogen sequence: SSGLPRNTVV LFVPQQEAWV VERMGRFHRI LEPGLNILIP VLDRIRYVQS LKEIVINVPE QSAVTLDNVT LQIDGVLYLR IMDPYKASYG VEDPEYAVTQ LAQTTMRSEL GKLSLDKVFR ERESLNASIV DAINQAADCW GIRCLRYEIK DIHVPPRVKE SMQMQVEAER RKRATVLESE GTRESAINVA EGKKQAQILA SEAEKAEQIN QAAGEASAVL AKAKAKAEAI RILAAALTQH NGDAAASLTV AEQYVSAFSK LAKDSNTILL PSNPGDVTSM VAQAMGVYGA LTKAPVPGTP DSLSSGSSRD VQGTDASLDE ELDRVKMS; Positive Samples: U-87MG, A375, A-549, B-cell, Mouse liver, Mouse kidney, Rat liver, Rat thymus; Cellular Location: Cell membrane, Membrane raft, Mitochondrion inner membrane, Mitochondrion intermembrane space, Peripheral membrane protein

Target Information

Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.