Thermo Fisher Scientific SYNPO2L Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (IHC)

20 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A 19 amino acid peptide near the amino terminus of human SYNPO2L. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SYNPO2L,uniProtId:Q9H987-1,ncbiNodeId:9606,antigenRange:1,antigenLength:977,antigenImageFileName:PA5-21056_SYNPO2L_Q9H987-1_Rabbit.svg,antigenImageFileNamePDP:PA5-21056_SYNPO2L_Q9H987-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11155844

Product Specific Information

A suggested positive control is human thymus tissue lysate.

PA5-21056 can be used with blocking peptide PEP-1170.

Target Information

SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.